Prazipro Timing and Duration with TTM

[Johnseye]

I've seen various suggestions regarding when to use Prazipro during TTM. Some do it on the 1st and 4th transfers and and some on day 1 then again on day 10. If a treatment of Prazipro is intended to last 5-7 days why not use it for 6 days or two cycles of the TTM. For instance start on day 1 and include it in the next transfer, but stop after the 2nd transfer or 3rd tank of water? That should be about 6 days total.

I can understand some won't want to start it on day 1 but wait until the fish start eating but the same principle would apply. What's the point of a shorter than recommended time frame?

[scooter31707]

Yes, you will read different opinions on this topic. Me, I dose on the 2nd and 3rd transfers. Reasoning being, I try and make sure the fish are eating before dosing the PP, as it is known to suppress appetites.

[MrsReefK]

Originally Posted by scooter31707

Yes, you will read different opinions on this topic. Me, I dose on the 2nd and 3rd transfers. Reasoning being, I try and make sure the fish are eating before dosing the PP, as it is known to suppress appetites.

I do the identical way as you, same reasoning, making sure they're eating first.


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[m0nkie]

Prazi only works for a day or two and the medication effect is gone. You wait a few days in between to catch the hatching eggs

[Spar]

Originally Posted by m0nkie

You wait a few days in between to catch the hatching eggs

^^this

doing doses on transfers 2 and 3 wont provide enough time for eggs to hatch. i would need to go dig up the actual life cycle on flukes, but if i recall right it was something like 5 days minimum. maturing flukes won't lay eggs again for something like 30 days, so you have a long period of time before a 2nd dose actually needs to be administered.

[Dmorty217]

Here is a tool you can use that will let you know exactly when to retreat based off of your temperature and salinity.

http://marineparasites.com/paratreatmentcal.html

[Deinonych]

^^^ Great link! Will start pointing folks to it.

[Dmorty217]

Originally Posted by Deinonych

^^^ Great link! Will start pointing folks to it.

I credit Humblefish, he gave it to me

[Johnseye]

Originally Posted by Dmorty217

Here is a tool you can use that will let you know exactly when to retreat based off of your temperature and salinity.

http://marineparasites.com/paratreatmentcal.html

According to that site, at 79F and 35%, if treatment takes place on day 1 then it should take place again on day 7, or after 6 days. When using Prazi, how long should the treatment last? According to what's being stated in this thread, when using the TTM one would want to administer, skip adding it on the next transfer, then administer Prazi on the following.

[Spar]

Originally Posted by Johnseye

According to what's being stated in this thread, when using the TTM one would want to administer, skip adding it on the next transfer, then administer Prazi on the following.

this

[Newms118]

Originally Posted by m0nkie

Prazi only works for a day or two and the medication effect is gone. You wait a few days in between to catch the hatching eggs

Wait, what??

I have persistant flukes as we speak, on round 2 and still having a clownfish with flukes attached, having to dip to get them off otherwise it seems to get swarmed by them.

I'm about to change out water and do round 3 of Prazipro. So your suggesting you should wait a few days? I always thought this was like Ick, have to keep drug in water at all times.

[Newms118]

So going off of what has been shown here, at 35% salinity and 79 degrees F, the treatment should be replaced every 6 days rather than the 5 the bottle says to do. So here is my issue, I have been doing every 5, and if the drug is only present for 2 days (or at least is effective for 2 days), how to do know when to add the drug if I'm already on a second cycle? Should I assume the second cycle did nothing and just go off of when the first dose was given or just forget what cycle I am on and just replace drug every 6 day from now on?

[Spar]

In most peoples experience a single dosage will kill all hatched-flukes currently present in the tank, almost immediately but definately within the 2 days that the PP is 'good for'. It will not kill the eggs. The eggs at the time of the first dosage will hatch up to and within 6 days. The second dose will kill all the new hatchlings.

You likely aren't experiencing flukes if your Clown is still covered in them after your first dose. That or your PP bottle is bad. I know taking a picture of flukes is difficult, but try to get a good snap of your Clown and see what people think.

[Newms118]

Originally Posted by Spar

In most peoples experience a single dosage will kill all hatched-flukes currently present in the tank, almost immediately but definately within the 2 days that the PP is 'good for'. It will not kill the eggs. The eggs at the time of the first dosage will hatch up to and within 6 days. The second dose will kill all the new hatchlings.

You likely aren't experiencing flukes if your Clown is still covered in them after your first dose. That or your PP bottle is bad. I know taking a picture of flukes is difficult, but try to get a good snap of your Clown and see what people think.

Will do.

Here is some previous pics that I took before starting PP. I was instructed to dip the fish, which I did in Paraguard (never did a FW dip, last time I tried making the water I struggled getting the pH correct). After the dip and a round of PP, many of these spots fell off/went away. Its just that I recently saw it flashing and upon inspection, saw these spots again. Ill post up a good pic later today.







I should add I also have 40 mg / gallon CP in the water with the PP.

[Spar]

do those spots look more like abrasions, or is it obvious it is something latching onto the outer layer of skin? hard to tell in the photos, but to me it looks more like abrasions on the skin.

hopefully someone with more experience with bacterial infections can jump in, but that is where my mind is at. if it were brook I think you'd something more dire at this point.

[Newms118]

Originally Posted by Spar

do those spots look more like abrasions, or is it obvious it is something latching onto the outer layer of skin? hard to tell in the photos, but to me it looks more like abrasions on the skin.

hopefully someone with more experience with bacterial infections can jump in, but that is where my mind is at. if it were brook I think you'd something more dire at this point.

Those pics are bad I know. At first I thought it was Ick bc some of them had a little spot on top. But the spot isnt white, more translucent (like a sugar crystal) than anything. And near the gills, the fish had some green spots, but maybe thats just slime. It kept scratching at the gills.

If it was brook, wouldnt the CP treat it as well?

[tassod]

It took 7 treatments to finally kill flukes in my fish, only after following the treatment cycle in the link posted I was finally able to kill the eggs that hatched. I also always double the dose.

[Newms118]

Originally Posted by tassod

It took 7 treatments to finally kill flukes in my fish, only after following the treatment cycle in the link posted I was finally able to kill the eggs that hatched. I also always double the dose.

so you treat at a final concentration of 5 mg / L?

Well I'm going to try the schedule and see what happens.

[Dmorty217]

Originally Posted by Newms118

so you treat at a final concentration of 5 mg / L?

Well I'm going to try the schedule and see what happens.

Yes he had been. I was dealing with prazipro resistant fluke also. I text with Tasso about the whole ordeal. I treated somewhere in the neighborhood of 12-15 times to finally kill the flukes. Concentrations up to 8mg/g, fish handled it without issue

[Newms118]

Originally Posted by Dmorty217

Yes he had been. I was dealing with prazipro resistant fluke also. I text with Tasso about the whole ordeal. I treated somewhere in the neighborhood of 12-15 times to finally kill the flukes. Concentrations up to 8mg/g, fish handled it without issue

What about if CP was given at the same time?

[Johnseye]

I administered the first dose of Prazi as a prophylactic at the last TTM cycle. Placed fish (two Bartlett Anthias) into a more permanent QT with bio filter, waited a week then administered a second round of Prazi. Considering Prazi is only active a couple days, killing any potential pests, would it be safe to move the fish into the DT only after a couple days of the final Prazi treatment as opposed to the 5-7 considering this is the final treatment?

[Dmorty217]

Prazipro is rendered useless in 72 hrs, probably closer to 48 hrs. The flukes should all spasm off the infected fish within the first 24 hrs or the dosage isn't strong enough

[Dmorty217]

Originally Posted by Newms118

What about if CP was given at the same time?

CP won't do anything for flukes, no matter what the dose. When I use PP now, I redose every 3 days for 2 weeks straight to make sure there is no way some newly hatched flukes can make it to sexual maturity

[Dmorty217]

Originally Posted by Newms118

Will do.

Here is some previous pics that I took before starting PP. I was instructed to dip the fish, which I did in Paraguard (never did a FW dip, last time I tried making the water I struggled getting the pH correct). After the dip and a round of PP, many of these spots fell off/went away. Its just that I recently saw it flashing and upon inspection, saw these spots again. Ill post up a good pic later today.







I should add I also have 40 mg / gallon CP in the water with the PP.

Those are flukes all over the clowns, freshwater or formalin dip them and watch the white flakes start to fly

[firemountain]

Originally Posted by scooter31707

Yes, you will read different opinions on this topic. Me, I dose on the 2nd and 3rd transfers. Reasoning being, I try and make sure the fish are eating before dosing the PP, as it is known to suppress appetites.

Echo this. +1